Cinnamic acids and derivatives
Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | MFCD00236450 | 99.3% | 10 MG
Tyrphostin AG 879 is a small-molecule tyrosine kinase inhibitor widely used in laboratory research. It shows selectivity for ErbB2 (HER2) with a reported IC50 of about 1 μM and reduces TrkA phosphorylation at higher micromolar concentrations. The compound is supplied as a powder, is soluble in DMSO, and is intended for in vitro signaling and kinase pathway studies.
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 99.2% | C14H15N3O5 | 10MG
Entacapone (Standard) is an analytical reference standard of entacapone (CAS 130929-57-6) supplied for research and analytical applications. It is intended for use in qualitative and quantitative assays, method development, and validation for chromatographic and mass spectrometric techniques.
- Provides a certified analytical standard for assay development and method validation.
- High purity reference material (≈99.2%).
- Suitable for HPLC, GC, and MS applications.
- Light yellow solid, stable under recommended storage conditions.
- Supports studies of catechol-O-methyltransferase activity and Parkinson's disease research.
Medchemexpress LLC Tyrphostin 8 | 3785-90-8 | MFCD00020189 | 98.0% | 170.17 g/mol | C10H6N2O | 10 MG
Tyrphostin 8 is a small-molecule tyrosine kinase inhibitor used as a research reagent to investigate EGFR signaling and related pathways. The compound is supplied as a light yellow to yellow solid with high reported purity and is offered in multiple solid sizes and DMSO solution formats.
- Inhibits EGFR kinase; reported IC50 ≈ 560 μM
- Also exhibits GTPase inhibitory activity
- High purity for reproducible experimental results
- Available as solid and as 10 mM DMSO solution in multiple sizes
- Storage recommended: solid at 4°C under nitrogen; solutions at -80°C or -20°C
TARGETMOL CHEMICALS INC SAR405 R enantiomer 5MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34. Purity 98.04%
Sigma Aldrich Fine Chemicals Biosciences Rivaroxaban R enantiomer U20MG
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MG
SAR405 R enantiomer is the less active stereoisomer of the PIK3C3/Vps34 inhibitor SAR405, provided as a solid for in vitro research use only. It is suited for comparative pharmacology and control studies and includes handling and storage guidance for reliable experimental use.
- Less active enantiomer used as a comparative control in assays.
- High purity (≈99.9%).
- Solid, white to off-white appearance.
- Molecular formula C19H21ClF3N5O2; molecular weight 443.85.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store powder at -20°C for long-term stability; store solutions at -80°C.
- Intended for laboratory research use only.
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 100mg
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Cayman Chemical m-CoumarIc AcId 10g
An active metabolite of polyphenols; inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM); induces neurite outgrowth of fetal rat hippocampal neurons at 10 µM; induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cells at 5 and 10 mM, respectively; increases locomotor activity in mice at 3 mmol/kg
Medchemexpress LLC 2-acetamido-3-phenylprop-2-enoic acid | 5469-45-4 | MFCD00188416 | 99.5% | 205.21 g·mol⁻¹ | C11H11NO3 | 25 G
α-Acetamidocinnamic acid is an alkaloid-derived research reagent (CAS 5469-45-4) used in biochemical and natural product studies. It is supplied as a high-purity solid for use as a reference compound, synthetic building block, or analytical standard. Certificate of analysis and safety data sheet are available.
- CAS number 5469-45-4.
- Molecular formula C11H11NO3.
- Molecular weight 205.21 g·mol⁻¹.
- Purity 99.5%.
- Supplied as a solid.
- Available pack sizes: 25 g, 50 g, 100 g.
- Certificate of analysis and safety data sheet available.
Apexbio Technology LLC Tyrphostin 9 10537-47-0 10mM (in 1mL DMSO)
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Medchemexpress LLC Tyrphostin A9 | 10537-47-0 | MFCD00209853 | 99.9% | 282.38 g/mol | C18H22N2O | 10 MG
Tyrphostin A9 is a small-molecule PDGFR inhibitor provided as an analytical standard for research applications. It is used in biochemical and cell-based studies to investigate tyrosine kinase signaling and mitochondrial dynamics. The material is supplied with purity and storage information and is available in multiple solid and solution formats for laboratory use.
- High purity suitable for analytical and research use.
- Useful as a PDGFR and tyrosine kinase inhibitor in cell and biochemical assays.
- Available in solid and solution formats for flexible experimental workflows.
- Documented stability when stored under recommended conditions.
- Supplied with supporting documentation such as a certificate of analysis or data sheet.
Apexbio Technology LLC Entacapone 130929-57-6 100mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Med Vet International Fluoxetine, 20mg, 30 Tablets
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Fluoxetine is a generic form of PROZac and is an SSRI antidepressant. It affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive disorder.